PATZ1 induces PP4R2 to form a negative feedback loop on IKK/NF-κB signaling in lung cancer

Activation of IKK enhances NF-κB signaling to facilitate cancer cell migration, invasion and metastasis. Here, we uncover the existence of a negative feedback loop of IKK. The transcription factor PATZ1 induces protein phosphatase-4 (PP4) regulatory subunit 2 (PP4R2) in an IKK-dependent manner. PP4R...

Descripción completa

Detalles Bibliográficos
Autores principales: Ho, Ming-Yi, Liang, Chi-Ming, Liang, Shu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239549/
https://www.ncbi.nlm.nih.gov/pubmed/27391343
http://dx.doi.org/10.18632/oncotarget.10427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239549/
https://www.ncbi.nlm.nih.gov/pubmed/27391343
http://dx.doi.org/10.18632/oncotarget.10427

Ejemplares similares