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Up-regulation of fibroblast growth factor 19 and its receptor associates with progression from fatty liver to hepatocellular carcinoma

BACKGROUND: Human fibroblast growth factor 19 (FGF19), its receptor (FGFR4) and EpCAM play an important role in cell proliferation, differentiation, motility, and overexpression have been linked to hepatocellular carcinoma (HCC). The aim of this study was to evaluate the FGF19 signals responsible fo...

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Detalles Bibliográficos
Autores principales: Li, Yan, Zhang, Weizhong, Doughtie, Anne, Cui, Guozhen, Li, Xuanyi, Pandit, Harshul, Yang, Yingbin, Li, Suping, Martin, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239555/
https://www.ncbi.nlm.nih.gov/pubmed/27447573
http://dx.doi.org/10.18632/oncotarget.10750