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MicroRNA-184 promotes differentiation of the retinal pigment epithelium by targeting the AKT2/mTOR signaling pathway

Dedifferentiation of retinal pigment epithelium (RPE) cells is a crucial contributing factor to the pathology of retinal degenerative diseases, including age-related macular degeneration (AMD). Herein, we aim to reveal the roles of microRNAs (miRNAs) in RPE dedifferentiation and seek for potential t...

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Detalles Bibliográficos
Autores principales: Jiang, Chao, Qin, Bing, Liu, Guohua, Sun, Xiantao, Shi, Houxia, Ding, Sijia, Liu, Yuan, Zhu, Meidong, Chen, Xue, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239556/
https://www.ncbi.nlm.nih.gov/pubmed/27418134
http://dx.doi.org/10.18632/oncotarget.10566