Disruption of tumour-host communication by downregulation of LFA-1 reduces COX-2 and e-NOS expression and inhibits brain metastasis growth

Over 20% of cancer patients will suffer metastatic spread to the brain, and prognosis remains poor. Communication between tumour cells and host tissue is essential during metastasis, yet little is known of the processes underlying such interactions in the brain. Here we test the hypothesis that cros...

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Detalles Bibliográficos
Autores principales: Soto, Manuel Sarmiento, O'Brien, Emma R., Andreou, Kleopatra, Scrace, Simon F., Zakaria, Rasheed, Jenkinson, Michael D., O'Neill, Eric, Sibson, Nicola R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239559/
https://www.ncbi.nlm.nih.gov/pubmed/27447568
http://dx.doi.org/10.18632/oncotarget.10737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239559/
https://www.ncbi.nlm.nih.gov/pubmed/27447568
http://dx.doi.org/10.18632/oncotarget.10737

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