FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance

The FAM83 proteins were recently identified as novel transforming oncogenes that function as intermediaries in EGFR/RAS signaling. Using two distinct forward genetics screens, the Bissell and Jackson laboratories uncovered the importance of the FAM83 proteins in promoting resistance to EGFR tyrosine...

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Detalles Bibliográficos
Autores principales: Bartel, Courtney A., Parameswaran, Neetha, Cipriano, Rocky, Jackson, Mark W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239576/
https://www.ncbi.nlm.nih.gov/pubmed/27221039
http://dx.doi.org/10.18632/oncotarget.9544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239576/
https://www.ncbi.nlm.nih.gov/pubmed/27221039
http://dx.doi.org/10.18632/oncotarget.9544

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