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FAM83 proteins: Fostering new interactions to drive oncogenic signaling and therapeutic resistance

The FAM83 proteins were recently identified as novel transforming oncogenes that function as intermediaries in EGFR/RAS signaling. Using two distinct forward genetics screens, the Bissell and Jackson laboratories uncovered the importance of the FAM83 proteins in promoting resistance to EGFR tyrosine...

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Detalles Bibliográficos
Autores principales:	Bartel, Courtney A., Parameswaran, Neetha, Cipriano, Rocky, Jackson, Mark W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239576/ https://www.ncbi.nlm.nih.gov/pubmed/27221039 http://dx.doi.org/10.18632/oncotarget.9544

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