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Modulation of proteostasis by transcription factor NRF2 and impact in neurodegenerative diseases

Neurodegenerative diseases are linked to the accumulation of specific protein aggregates, suggesting an intimate connection between injured brain and loss of proteostasis. Proteostasis refers to all the processes by which cells control the abundance and folding of the proteome thanks to a wide netwo...

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Detalles Bibliográficos
Autores principales: Pajares, Marta, Cuadrado, Antonio, Rojo, Ana I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239825/
https://www.ncbi.nlm.nih.gov/pubmed/28104575
http://dx.doi.org/10.1016/j.redox.2017.01.006