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Ursodeoxycholic Acid Attenuates Endoplasmic Reticulum Stress-Related Retinal Pericyte Loss in Streptozotocin-Induced Diabetic Mice

Loss of pericytes, an early hallmark of diabetic retinopathy (DR), results in breakdown of the blood-retinal barrier. Endoplasmic reticulum (ER) stress may be involved in this process. The purpose of this study was to examine the effects of ursodeoxycholic acid (UDCA), a known ameliorator of ER stre...

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Detalles Bibliográficos
Autores principales: Chung, Yoo-Ri, Choi, Jeong A., Koh, Jae-Young, Yoon, Young Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239976/
https://www.ncbi.nlm.nih.gov/pubmed/28127564
http://dx.doi.org/10.1155/2017/1763292