Unloading of homologous recombination factors is required for restoring double‐stranded DNA at damage repair loci

Cells use homology‐dependent DNA repair to mend chromosome breaks and restore broken replication forks, thereby ensuring genome stability and cell survival. DNA break repair via homology‐based mechanisms involves nuclease‐dependent DNA end resection, which generates long tracts of single‐stranded DN...

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Detalles Bibliográficos
Autores principales: Vasianovich, Yulia, Altmannova, Veronika, Kotenko, Oleksii, Newton, Matthew D, Krejci, Lumir, Makovets, Svetlana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239998/
https://www.ncbi.nlm.nih.gov/pubmed/27932447
http://dx.doi.org/10.15252/embj.201694628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239998/
https://www.ncbi.nlm.nih.gov/pubmed/27932447
http://dx.doi.org/10.15252/embj.201694628

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