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Unloading of homologous recombination factors is required for restoring double‐stranded DNA at damage repair loci
Cells use homology‐dependent DNA repair to mend chromosome breaks and restore broken replication forks, thereby ensuring genome stability and cell survival. DNA break repair via homology‐based mechanisms involves nuclease‐dependent DNA end resection, which generates long tracts of single‐stranded DN...
Autores principales: | Vasianovich, Yulia, Altmannova, Veronika, Kotenko, Oleksii, Newton, Matthew D, Krejci, Lumir, Makovets, Svetlana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5239998/ https://www.ncbi.nlm.nih.gov/pubmed/27932447 http://dx.doi.org/10.15252/embj.201694628 |
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