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Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway

Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in vivo. The results showed that a fucoidan KW derived from...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Wu, Jiandong, Zhang, Xiaoshuang, Hao, Cui, Zhao, Xiaoliang, Jiao, Guangling, Shan, Xindi, Tai, Wenjing, Yu, Guangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240104/
https://www.ncbi.nlm.nih.gov/pubmed/28094330
http://dx.doi.org/10.1038/srep40760