Cargando…
Inhibition of Influenza A Virus Infection by Fucoidan Targeting Viral Neuraminidase and Cellular EGFR Pathway
Development of novel anti-influenza A virus (IAV) drugs with high efficiency and low toxicity is critical for preparedness against influenza outbreaks. Herein, we investigated the anti-IAV activities and mechanisms of fucoidan in vitro and in vivo. The results showed that a fucoidan KW derived from...
Autores principales: | Wang, Wei, Wu, Jiandong, Zhang, Xiaoshuang, Hao, Cui, Zhao, Xiaoliang, Jiao, Guangling, Shan, Xindi, Tai, Wenjing, Yu, Guangli |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240104/ https://www.ncbi.nlm.nih.gov/pubmed/28094330 http://dx.doi.org/10.1038/srep40760 |
Ejemplares similares
-
Fucoidan from Ascophyllum
nodosum Suppresses Postprandial Hyperglycemia by Inhibiting Na(+)/Glucose Cotransporter 1 Activity
por: Shan, Xindi, et al.
Publicado: (2020) -
Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling
por: Wang, Xueliang, et al.
Publicado: (2019) -
Influenza neuraminidase
por: Air, Gillian M.
Publicado: (2011) -
Identification of critical residues of influenza neuraminidase in viral particle release
por: Tisoncik, Jennifer R, et al.
Publicado: (2011) -
Identification of Chebulinic Acid and Chebulagic Acid as Novel Influenza Viral Neuraminidase Inhibitors
por: Li, Ping, et al.
Publicado: (2020)