Maternal diabetes modulates dental epithelial stem cells proliferation and self-renewal in offspring through apurinic/apyrimidinicendonuclease 1-mediated DNA methylation

Maternal gestational diabetes mellitus (GDM) has many adverse effects on the development of offspring. Aberrant DNA methylation is a potential mechanism associated with these effects. However, the effects of GDM on tooth development and the underlying mechanisms have not been thoroughly investigated...

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Detalles Bibliográficos
Autores principales: Chen, Guoqing, Chen, Jie, Yan, Zhiling, Li, Ziyue, Yu, Mei, Guo, Weihua, Tian, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240105/
https://www.ncbi.nlm.nih.gov/pubmed/28094306
http://dx.doi.org/10.1038/srep40762

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240105/
https://www.ncbi.nlm.nih.gov/pubmed/28094306
http://dx.doi.org/10.1038/srep40762

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