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Maternal diabetes modulates dental epithelial stem cells proliferation and self-renewal in offspring through apurinic/apyrimidinicendonuclease 1-mediated DNA methylation
Maternal gestational diabetes mellitus (GDM) has many adverse effects on the development of offspring. Aberrant DNA methylation is a potential mechanism associated with these effects. However, the effects of GDM on tooth development and the underlying mechanisms have not been thoroughly investigated...
Autores principales: | Chen, Guoqing, Chen, Jie, Yan, Zhiling, Li, Ziyue, Yu, Mei, Guo, Weihua, Tian, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240105/ https://www.ncbi.nlm.nih.gov/pubmed/28094306 http://dx.doi.org/10.1038/srep40762 |
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