Remission of lymphoblastic leukaemia in an intravascular fluidic environment by pliable drug carrier with a sliding target ligand

A polyrotaxane-based nanoconstruct with pliable structure carrying a chemotherapeutic drug was developed for targeting circulating lymphoblastic leukaemia cells in a fluidic environment of blood vessels in vivo. By introducing lymphoblast targeting aptamer DNA through cyclodextrin, threaded in poly(...

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Detalles Bibliográficos
Autores principales: Jang, Donghyun, Lee, Yeong Mi, Lee, Jaehyun, Doh, Junsang, Kim, Won Jong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240144/
https://www.ncbi.nlm.nih.gov/pubmed/28094326
http://dx.doi.org/10.1038/srep40739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240144/
https://www.ncbi.nlm.nih.gov/pubmed/28094326
http://dx.doi.org/10.1038/srep40739

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