Protein arginine methyltransferase 1 (PRMT1) represses MHC II transcription in macrophages by methylating CIITA

Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC...

Descripción completa

Detalles Bibliográficos
Autores principales: Fan, Zhiwen, Li, Jianfei, Li, Ping, Ye, Qing, Xu, Huihui, Wu, Xiaoyan, Xu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240148/
https://www.ncbi.nlm.nih.gov/pubmed/28094290
http://dx.doi.org/10.1038/srep40531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240148/
https://www.ncbi.nlm.nih.gov/pubmed/28094290
http://dx.doi.org/10.1038/srep40531

Ejemplares similares