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Protein arginine methyltransferase 1 (PRMT1) represses MHC II transcription in macrophages by methylating CIITA

Efficient presentation of alien antigens triggers activation of T lymphocytes and robust host defense against invading pathogens. This pathophysiological process relies on the expression of major histocompatibility complex (MHC) molecules in antigen presenting cells such as macrophages. Aberrant MHC...

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Detalles Bibliográficos
Autores principales:	Fan, Zhiwen, Li, Jianfei, Li, Ping, Ye, Qing, Xu, Huihui, Wu, Xiaoyan, Xu, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240148/ https://www.ncbi.nlm.nih.gov/pubmed/28094290 http://dx.doi.org/10.1038/srep40531

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