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PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression

BACKGROUND: Lobular carcinoma in situ (LCIS) is a non-invasive breast lesion that is typically found incidentally on biopsy and is often associated with invasive lobular carcinoma (ILC). LCIS is considered by some to be a risk factor for future breast cancer rather than a true precursor lesion. The...

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Detalles Bibliográficos
Autores principales: Shah, Vandna, Nowinski, Salpie, Levi, Dina, Shinomiya, Irek, Kebaier Ep Chaabouni, Narda, Gillett, Cheryl, Grigoriadis, Anita, Graham, Trevor A., Roylance, Rebecca, Simpson, Michael A., Pinder, Sarah E., Sawyer, Elinor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240238/
https://www.ncbi.nlm.nih.gov/pubmed/28095868
http://dx.doi.org/10.1186/s13058-016-0789-y