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Clinical and immunologic correlates of response to PD-1 blockade in a patient with metastatic renal medullary carcinoma

BACKGROUND: Renal medullary carcinoma (RMC) is a rare kidney tumor that occurs in adolescent and young adults, typically in association with sickle cell trait. RMC exhibits rapid disease progression, frequent metastases at diagnosis, and dismal clinical outcomes. Currently available therapies, inclu...

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Detalles Bibliográficos
Autores principales: Beckermann, Kathryn E., Jolly, Pradeep C., Kim, Ju Y., Bordeaux, Jennifer, Puzanov, Igor, Rathmell, W. Kimryn, Johnson, Douglas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240268/
https://www.ncbi.nlm.nih.gov/pubmed/28105368
http://dx.doi.org/10.1186/s40425-016-0206-1