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Kv7 voltage-activated potassium channel inhibitors reduce fluid resuscitation requirements after hemorrhagic shock in rats

BACKGROUND: Recent evidence suggests that drugs targeting Kv7 channels could be used to modulate vascular function and blood pressure. Here, we studied whether Kv7 channel inhibitors can be utilized to stabilize hemodynamics and reduce resuscitation fluid requirements after hemorrhagic shock. METHOD...

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Detalles Bibliográficos
Autores principales: Nassoiy, Sean P., Byron, Kenneth L., Majetschak, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240358/
https://www.ncbi.nlm.nih.gov/pubmed/28095830
http://dx.doi.org/10.1186/s12929-017-0316-1