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Insights into the design and interpretation of iCLIP experiments

BACKGROUND: Ultraviolet (UV) crosslinking and immunoprecipitation (CLIP) identifies the sites on RNAs that are in direct contact with RNA-binding proteins (RBPs). Several variants of CLIP exist, which require different computational approaches for analysis. This variety of approaches can create chal...

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Detalles Bibliográficos
Autores principales: Haberman, Nejc, Huppertz, Ina, Attig, Jan, König, Julian, Wang, Zhen, Hauer, Christian, Hentze, Matthias W., Kulozik, Andreas E., Le Hir, Hervé, Curk, Tomaž, Sibley, Christopher R., Zarnack, Kathi, Ule, Jernej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240381/
https://www.ncbi.nlm.nih.gov/pubmed/28093074
http://dx.doi.org/10.1186/s13059-016-1130-x