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Insights into the design and interpretation of iCLIP experiments
BACKGROUND: Ultraviolet (UV) crosslinking and immunoprecipitation (CLIP) identifies the sites on RNAs that are in direct contact with RNA-binding proteins (RBPs). Several variants of CLIP exist, which require different computational approaches for analysis. This variety of approaches can create chal...
Autores principales: | Haberman, Nejc, Huppertz, Ina, Attig, Jan, König, Julian, Wang, Zhen, Hauer, Christian, Hentze, Matthias W., Kulozik, Andreas E., Le Hir, Hervé, Curk, Tomaž, Sibley, Christopher R., Zarnack, Kathi, Ule, Jernej |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240381/ https://www.ncbi.nlm.nih.gov/pubmed/28093074 http://dx.doi.org/10.1186/s13059-016-1130-x |
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