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Link prediction in drug-target interactions network using similarity indices

BACKGROUND: In silico drug-target interaction (DTI) prediction plays an integral role in drug repositioning: the discovery of new uses for existing drugs. One popular method of drug repositioning is network-based DTI prediction, which uses complex network theory to predict DTIs from a drug-target ne...

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Detalles Bibliográficos
Autores principales: Lu, Yiding, Guo, Yufan, Korhonen, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240398/
https://www.ncbi.nlm.nih.gov/pubmed/28095781
http://dx.doi.org/10.1186/s12859-017-1460-z