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miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition

BACKGROUND: Despite advancements in the diagnosis and treatment of colorectal cancer (CRC), many patients die because of tumor metastasis or recurrence. Therefore, identifying new prognostic markers and elucidating the mechanisms of CRC metastasis and recurrence will help to improve the prognosis of...

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Detalles Bibliográficos
Autores principales: Zhao, Senlin, Sun, Hongcheng, Jiang, Weiliang, Mi, Yushuai, Zhang, Dongyuan, Wen, Yugang, Cheng, Dantong, Tang, Huamei, Wu, Shaohan, Yu, Yang, Liu, Xisheng, Cui, Weiyingqi, Zhang, Meng, Sun, Xiaofeng, Zhou, Zongguang, Peng, Zhihai, Yan, Dongwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240405/
https://www.ncbi.nlm.nih.gov/pubmed/28095858
http://dx.doi.org/10.1186/s12943-017-0585-z