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Random X-chromosome inactivation dynamics in vivo by single-cell RNA sequencing

BACKGROUND: Random X-chromosome inactivation (rXCI) is important for the maintenance of normal somatic cell functions in female eutherian mammals. The dynamics of X-chromosome inactivation initiation has been widely studied by assessing embryonic stem cell differentiation in vitro. To investigate th...

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Detalles Bibliográficos
Autores principales: Wang, Menghan, Lin, Fangqin, Xing, Ke, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240438/
https://www.ncbi.nlm.nih.gov/pubmed/28095777
http://dx.doi.org/10.1186/s12864-016-3466-8