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Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial

Background: Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid-β (Aβ) peptide between cerebrospinal fluid (CSF) and plasma compartments. Objective: To determine whether plasma exchange (PE) with albumin replacement was able to modify Aβ concentrati...

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Detalles Bibliográficos
Autores principales: Boada, Mercè, Anaya, Fernando, Ortiz, Pilar, Olazarán, Javier, Shua-Haim, Joshua R., Obisesan, Thomas O., Hernández, Isabel, Muñoz, Joan, Buendia, Mar, Alegret, Montserrat, Lafuente, Asunción, Tárraga, Lluís, Núñez, Laura, Torres, Mireia, Grifols, Joan Ramon, Ferrer, Isidre, Lopez, Oscar L., Páez, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240541/
https://www.ncbi.nlm.nih.gov/pubmed/27911295
http://dx.doi.org/10.3233/JAD-160565