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Efficacy and Safety of Plasma Exchange with 5% Albumin to Modify Cerebrospinal Fluid and Plasma Amyloid-β Concentrations and Cognition Outcomes in Alzheimer’s Disease Patients: A Multicenter, Randomized, Controlled Clinical Trial
Background: Studies conducted in animal models and humans suggest the presence of a dynamic equilibrium of amyloid-β (Aβ) peptide between cerebrospinal fluid (CSF) and plasma compartments. Objective: To determine whether plasma exchange (PE) with albumin replacement was able to modify Aβ concentrati...
Autores principales: | Boada, Mercè, Anaya, Fernando, Ortiz, Pilar, Olazarán, Javier, Shua-Haim, Joshua R., Obisesan, Thomas O., Hernández, Isabel, Muñoz, Joan, Buendia, Mar, Alegret, Montserrat, Lafuente, Asunción, Tárraga, Lluís, Núñez, Laura, Torres, Mireia, Grifols, Joan Ramon, Ferrer, Isidre, Lopez, Oscar L., Páez, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240541/ https://www.ncbi.nlm.nih.gov/pubmed/27911295 http://dx.doi.org/10.3233/JAD-160565 |
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