Cocaine Enhances DC to T-cell HIV-1 Transmission by Activating DC-SIGN/LARG/LSP1 Complex and Facilitating Infectious Synapse Formation

DC-SIGN is a dendritic cell surface structure which participates in binding and transmission of HIV-1. Here, for the first time we demonstrate that cocaine induces over expression of DC-SIGN and significantly enhances virus transfer from DCs to T-cells by increasing the binding and internalization o...

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Detalles Bibliográficos
Autores principales: Prasad, Anil, Kulkarni, Rutuja, Jiang, Shuxian, Groopman, Jerome E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240552/
https://www.ncbi.nlm.nih.gov/pubmed/28094782
http://dx.doi.org/10.1038/srep40648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240552/
https://www.ncbi.nlm.nih.gov/pubmed/28094782
http://dx.doi.org/10.1038/srep40648

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