A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics

Cells acquire the invasive and migratory properties necessary for the invasion-metastasis cascade and the establishment of aggressive, metastatic disease by reactivating a latent embryonic programme: epithelial-to-mesenchymal transition (EMT). Herein, we report the development of a new, spontaneous...

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Detalles Bibliográficos
Autores principales: Harner-Foreman, Naomi, Vadakekolathu, Jayakumar, Laversin, Stéphanie A., Mathieu, Morgan G., Reeder, Stephen, Pockley, A. Graham, Rees, Robert C., Boocock, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240554/
https://www.ncbi.nlm.nih.gov/pubmed/28094783
http://dx.doi.org/10.1038/srep40633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240554/
https://www.ncbi.nlm.nih.gov/pubmed/28094783
http://dx.doi.org/10.1038/srep40633

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