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A novel spontaneous model of epithelial-mesenchymal transition (EMT) using a primary prostate cancer derived cell line demonstrating distinct stem-like characteristics
Cells acquire the invasive and migratory properties necessary for the invasion-metastasis cascade and the establishment of aggressive, metastatic disease by reactivating a latent embryonic programme: epithelial-to-mesenchymal transition (EMT). Herein, we report the development of a new, spontaneous...
Autores principales: | Harner-Foreman, Naomi, Vadakekolathu, Jayakumar, Laversin, Stéphanie A., Mathieu, Morgan G., Reeder, Stephen, Pockley, A. Graham, Rees, Robert C., Boocock, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240554/ https://www.ncbi.nlm.nih.gov/pubmed/28094783 http://dx.doi.org/10.1038/srep40633 |
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