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Activation of Wnt/β-catenin signalling via GSK3 inhibitors direct differentiation of human adipose stem cells into functional hepatocytes

The generation of hepatocytes that are derived from human adipose stem cells (hASCs) represents an alternative to human hepatocytes for individualized therapeutic and pharmaceutical applications. However, the mechanisms facilitating hepatocyte differentiation from hASCs are not well understood. Here...

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Detalles Bibliográficos
Autores principales: Huang, Jieqiong, Guo, Xinyue, Li, Weihong, Zhang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240561/
https://www.ncbi.nlm.nih.gov/pubmed/28094799
http://dx.doi.org/10.1038/srep40716