Detection of a phosphorylated glycine-serine linker in an IgG-based fusion protein

Molecular mass determination by electrospray ionization mass spectrometry of a recombinant IgG-based fusion protein (mAb1-F) produced in human embryonic kidney (HEK) cells demonstrated the presence of a dominant +79 Da product variant. Using LC-MS tryptic peptide mapping analysis and collision-induc...

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Detalles Bibliográficos
Autores principales: Tyshchuk, Oksana, Völger, Hans Rainer, Ferrara, Claudia, Bulau, Patrick, Koll, Hans, Mølhøj, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240648/
https://www.ncbi.nlm.nih.gov/pubmed/27661266
http://dx.doi.org/10.1080/19420862.2016.1236165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240648/
https://www.ncbi.nlm.nih.gov/pubmed/27661266
http://dx.doi.org/10.1080/19420862.2016.1236165

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