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Stability of isolated antibody-antigen complexes as a predictive tool for selecting toxin neutralizing antibodies

Ricin is an A-B ribosome inactivating protein (RIP) toxin composed of an A-chain subunit (RTA) that contains a catalytic N-glycosidase and a B-chain (RTB) lectin domain that binds cell surface glycans. Ricin exploits retrograde transport to enter into the Golgi and the endoplasmic reticulum, and the...

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Detalles Bibliográficos
Autores principales: Legler, Patricia M., Compton, Jaimee R., Hale, Martha L., Anderson, George P., Olson, Mark A., Millard, Charles B., Goldman, Ellen R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240650/
https://www.ncbi.nlm.nih.gov/pubmed/27660893
http://dx.doi.org/10.1080/19420862.2016.1236882