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Novel multispecific heterodimeric antibody format allowing modular assembly of variable domain fragments

Multispecific antibody formats provide a promising platform for the development of novel therapeutic concepts that could facilitate the generation of safer, more effective pharmaceuticals. However, the production and use of such antibody-based multispecifics is often made complicated by: 1) the inst...

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Detalles Bibliográficos
Autores principales: Egan, Timothy J., Diem, Dania, Weldon, Richard, Neumann, Tessa, Meyer, Sebastian, Urech, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240654/
https://www.ncbi.nlm.nih.gov/pubmed/27786600
http://dx.doi.org/10.1080/19420862.2016.1248012