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The Nuclear Receptor HIZR-1 Uses Zinc as a Ligand to Mediate Homeostasis in Response to High Zinc

Nuclear receptors were originally defined as endocrine sensors in humans, leading to the identification of the nuclear receptor superfamily. Despite intensive efforts, most nuclear receptors have no known ligand, suggesting new ligand classes remain to be discovered. Furthermore, nuclear receptors a...

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Detalles Bibliográficos
Autores principales: Warnhoff, Kurt, Roh, Hyun C., Kocsisova, Zuzana, Tan, Chieh-Hsiang, Morrison, Andrew, Croswell, Damari, Schneider, Daniel L., Kornfeld, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240932/
https://www.ncbi.nlm.nih.gov/pubmed/28095401
http://dx.doi.org/10.1371/journal.pbio.2000094