Substrate Stiffness Controls Osteoblastic and Chondrocytic Differentiation of Mesenchymal Stem Cells without Exogenous Stimuli

Stem cell fate has been linked to the mechanical properties of their underlying substrate, affecting mechanoreceptors and ultimately leading to downstream biological response. Studies have used polymers to mimic the stiffness of extracellular matrix as well as of individual tissues and shown mesench...

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Detalles Bibliográficos
Autores principales: Olivares-Navarrete, Rene, Lee, Erin M., Smith, Kathryn, Hyzy, Sharon L., Doroudi, Maryam, Williams, Joseph K., Gall, Ken, Boyan, Barbara D., Schwartz, Zvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240960/
https://www.ncbi.nlm.nih.gov/pubmed/28095466
http://dx.doi.org/10.1371/journal.pone.0170312

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240960/
https://www.ncbi.nlm.nih.gov/pubmed/28095466
http://dx.doi.org/10.1371/journal.pone.0170312

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