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Structural snapshots of Xer recombination reveal activation by synaptic complex remodeling and DNA bending

Bacterial Xer site-specific recombinases play an essential genome maintenance role by unlinking chromosome multimers, but their mechanism of action has remained structurally uncharacterized. Here, we present two high-resolution structures of Helicobacter pylori XerH with its recombination site DNA d...

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Detalles Bibliográficos
Autores principales: Bebel, Aleksandra, Karaca, Ezgi, Kumar, Banushree, Stark, W Marshall, Barabas, Orsolya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241119/
https://www.ncbi.nlm.nih.gov/pubmed/28009253
http://dx.doi.org/10.7554/eLife.19706