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Evaluation of a 2-aminoimidazole variant as adjuvant treatment for dermal bacterial infections

2-Aminoimidazole (2-AI)-based compounds have been shown to efficiently disrupt biofilm formation, disperse existing biofilms, and resensitize numerous multidrug-resistant bacteria to antibiotics. Using Pseudomonas aeruginosa and Staphylococcus aureus, we provide initial pharmacological studies regar...

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Detalles Bibliográficos
Autores principales: Draughn, G Logan, Allen, C Leigh, Routh, Patricia A, Stone, Maria R, Kirker, Kelly R, Boegli, Laura, Schuchman, Ryan M, Linder, Keith E, Baynes, Ronald E, James, Garth, Melander, Christian, Pollard, Angela, Cavanagh, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241126/
https://www.ncbi.nlm.nih.gov/pubmed/28138218
http://dx.doi.org/10.2147/DDDT.S111865