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Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting

Computational neutralization fingerprinting, NFP, is an efficient and accurate method for predicting the epitope specificities of polyclonal antibody responses to HIV-1 infection. Here, we present next-generation NFP algorithms that substantially improve prediction accuracy for individual donors and...

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Detalles Bibliográficos
Autores principales: Doria-Rose, Nicole A., Altae-Tran, Han R., Roark, Ryan S., Schmidt, Stephen D., Sutton, Matthew S., Louder, Mark K., Chuang, Gwo-Yu, Bailer, Robert T., Cortez, Valerie, Kong, Rui, McKee, Krisha, O’Dell, Sijy, Wang, Felicia, Abdool Karim, Salim S., Binley, James M., Connors, Mark, Haynes, Barton F., Martin, Malcolm A., Montefiori, David C., Morris, Lynn, Overbaugh, Julie, Kwong, Peter D., Mascola, John R., Georgiev, Ivelin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241146/
https://www.ncbi.nlm.nih.gov/pubmed/28052137
http://dx.doi.org/10.1371/journal.ppat.1006148