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Mapping Polyclonal HIV-1 Antibody Responses via Next-Generation Neutralization Fingerprinting
Computational neutralization fingerprinting, NFP, is an efficient and accurate method for predicting the epitope specificities of polyclonal antibody responses to HIV-1 infection. Here, we present next-generation NFP algorithms that substantially improve prediction accuracy for individual donors and...
Autores principales: | Doria-Rose, Nicole A., Altae-Tran, Han R., Roark, Ryan S., Schmidt, Stephen D., Sutton, Matthew S., Louder, Mark K., Chuang, Gwo-Yu, Bailer, Robert T., Cortez, Valerie, Kong, Rui, McKee, Krisha, O’Dell, Sijy, Wang, Felicia, Abdool Karim, Salim S., Binley, James M., Connors, Mark, Haynes, Barton F., Martin, Malcolm A., Montefiori, David C., Morris, Lynn, Overbaugh, Julie, Kwong, Peter D., Mascola, John R., Georgiev, Ivelin S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241146/ https://www.ncbi.nlm.nih.gov/pubmed/28052137 http://dx.doi.org/10.1371/journal.ppat.1006148 |
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