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Identification and functional analysis of c.422_423InsT, a novel mutation of the HNF1A gene in a patient with diabetes
BACKGROUND: HNF1A gene regulates liver‐specific genes, and genes that have a role in glucose metabolism, transport, and secretion of insulin. HNF1A gene mutations are frequently associated with type 2 diabetes. HNF1A protein has three domains: the dimerization domain, the DNA‐binding domain, and the...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241209/ https://www.ncbi.nlm.nih.gov/pubmed/28116330 http://dx.doi.org/10.1002/mgg3.261 |