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Transcription Factor EB Controls Metabolic Flexibility during Exercise

The transcription factor EB (TFEB) is an essential component of lysosomal biogenesis and autophagy for the adaptive response to food deprivation. To address the physiological function of TFEB in skeletal muscle, we have used muscle-specific gain- and loss-of-function approaches. Here, we show that T...

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Detalles Bibliográficos
Autores principales: Mansueto, Gelsomina, Armani, Andrea, Viscomi, Carlo, D’Orsi, Luca, De Cegli, Rossella, Polishchuk, Elena V., Lamperti, Costanza, Di Meo, Ivano, Romanello, Vanina, Marchet, Silvia, Saha, Pradip K., Zong, Haihong, Blaauw, Bert, Solagna, Francesca, Tezze, Caterina, Grumati, Paolo, Bonaldo, Paolo, Pessin, Jeffrey E., Zeviani, Massimo, Sandri, Marco, Ballabio, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241227/
https://www.ncbi.nlm.nih.gov/pubmed/28011087
http://dx.doi.org/10.1016/j.cmet.2016.11.003