Cargando…
Transcription Factor EB Controls Metabolic Flexibility during Exercise
The transcription factor EB (TFEB) is an essential component of lysosomal biogenesis and autophagy for the adaptive response to food deprivation. To address the physiological function of TFEB in skeletal muscle, we have used muscle-specific gain- and loss-of-function approaches. Here, we show that T...
Autores principales: | Mansueto, Gelsomina, Armani, Andrea, Viscomi, Carlo, D’Orsi, Luca, De Cegli, Rossella, Polishchuk, Elena V., Lamperti, Costanza, Di Meo, Ivano, Romanello, Vanina, Marchet, Silvia, Saha, Pradip K., Zong, Haihong, Blaauw, Bert, Solagna, Francesca, Tezze, Caterina, Grumati, Paolo, Bonaldo, Paolo, Pessin, Jeffrey E., Zeviani, Massimo, Sandri, Marco, Ballabio, Andrea |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241227/ https://www.ncbi.nlm.nih.gov/pubmed/28011087 http://dx.doi.org/10.1016/j.cmet.2016.11.003 |
Ejemplares similares
-
FGF21 as Modulator of Metabolism in Health and Disease
por: Tezze, Caterina, et al.
Publicado: (2019) -
AAV9-based gene therapy partially ameliorates the clinical phenotype of a mouse model of Leigh syndrome
por: Di Meo, I, et al.
Publicado: (2017) -
Fibroblast growth factor 21 controls mitophagy and muscle mass
por: Oost, Lynette J., et al.
Publicado: (2019) -
Effective AAV-mediated gene therapy in a mouse model of ethylmalonic encephalopathy
por: Di Meo, Ivano, et al.
Publicado: (2012) -
Autophagy in Skeletal Muscle Homeostasis and in Muscular Dystrophies
por: Grumati, Paolo, et al.
Publicado: (2012)