Repurposing Approach Identifies Auranofin with Broad Spectrum Antifungal Activity That Targets Mia40-Erv1 Pathway

Current antifungal therapies have limited effectiveness in treating invasive fungal infections. Furthermore, the development of new antifungal is currently unable to keep pace with the urgent demand for safe and effective new drugs. Auranofin, an FDA-approved drug for the treatment of rheumatoid art...

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Detalles Bibliográficos
Autores principales: Thangamani, Shankar, Maland, Matthew, Mohammad, Haroon, Pascuzzi, Pete E., Avramova, Larisa, Koehler, Carla M., Hazbun, Tony R., Seleem, Mohamed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241286/
https://www.ncbi.nlm.nih.gov/pubmed/28149831
http://dx.doi.org/10.3389/fcimb.2017.00004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241286/
https://www.ncbi.nlm.nih.gov/pubmed/28149831
http://dx.doi.org/10.3389/fcimb.2017.00004

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