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Inner Hair Cell Loss Disrupts Hearing and Cochlear Function Leading to Sensory Deprivation and Enhanced Central Auditory Gain

There are three times as many outer hair cells (OHC) as inner hair cells (IHC), yet IHC transmit virtually all acoustic information to the brain as they synapse with 90–95% of type I auditory nerve fibers. Here we review a comprehensive series of experiments aimed at determining how loss of the IHC/...

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Detalles Bibliográficos
Autores principales: Salvi, Richard, Sun, Wei, Ding, Dalian, Chen, Guang-Di, Lobarinas, Edward, Wang, Jian, Radziwon, Kelly, Auerbach, Benjamin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241314/
https://www.ncbi.nlm.nih.gov/pubmed/28149271
http://dx.doi.org/10.3389/fnins.2016.00621