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Glutamate and α-ketoglutarate: key players in glioma metabolism
Glioblastoma multiforme (GBM), or grade IV astrocytoma, is the most common type of primary brain tumor. It has a devastating prognosis with a 2-year-overall survival rate of only 26 % after standard treatment, which includes surgery, radiation, and adjuvant chemotherapy with temozolomide. Also lower...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Vienna
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241329/ https://www.ncbi.nlm.nih.gov/pubmed/27752843 http://dx.doi.org/10.1007/s00726-016-2342-9 |