Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity

Analysis of the incorporation of cellular microRNAs (miRNAs) into highly purified HIV-1 virions revealed that this largely, but not entirely, mirrored the level of miRNA expression in the producer CD4(+) T cells. Specifically, of the 58 cellular miRNAs detected at significant levels in the producer...

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Detalles Bibliográficos
Autores principales: Bogerd, Hal P., Kennedy, Edward M., Whisnant, Adam W., Cullen, Bryan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241401/
https://www.ncbi.nlm.nih.gov/pubmed/28096489
http://dx.doi.org/10.1128/mBio.02125-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241401/
https://www.ncbi.nlm.nih.gov/pubmed/28096489
http://dx.doi.org/10.1128/mBio.02125-16

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