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Induced Packaging of Cellular MicroRNAs into HIV-1 Virions Can Inhibit Infectivity
Analysis of the incorporation of cellular microRNAs (miRNAs) into highly purified HIV-1 virions revealed that this largely, but not entirely, mirrored the level of miRNA expression in the producer CD4(+) T cells. Specifically, of the 58 cellular miRNAs detected at significant levels in the producer...
Autores principales: | Bogerd, Hal P., Kennedy, Edward M., Whisnant, Adam W., Cullen, Bryan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241401/ https://www.ncbi.nlm.nih.gov/pubmed/28096489 http://dx.doi.org/10.1128/mBio.02125-16 |
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