Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis

For decades, identifying the regions of a bacterial chromosome that are necessary for viability has relied on mapping integration sites in libraries of random transposon mutants to find loci that are unable to sustain insertion. To date, these studies have analyzed subsaturated libraries, necessitat...

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Detalles Bibliográficos
Autores principales: DeJesus, Michael A., Gerrick, Elias R., Xu, Weizhen, Park, Sae Woong, Long, Jarukit E., Boutte, Cara C., Rubin, Eric J., Schnappinger, Dirk, Ehrt, Sabine, Fortune, Sarah M., Sassetti, Christopher M., Ioerger, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241402/
https://www.ncbi.nlm.nih.gov/pubmed/28096490
http://dx.doi.org/10.1128/mBio.02133-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241402/
https://www.ncbi.nlm.nih.gov/pubmed/28096490
http://dx.doi.org/10.1128/mBio.02133-16

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