Base changes in tumour DNA have the power to reveal the causes and evolution of cancer

Next-generation sequencing (NGS) technology has demonstrated that the cancer genomes are peppered with mutations. Although most somatic tumour mutations are unlikely to have any role in the cancer process per se, the spectra of DNA sequence changes in tumour mutation catalogues have the potential to...

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Detalles Bibliográficos
Autores principales: Hollstein, M, Alexandrov, L B, Wild, C P, Ardin, M, Zavadil, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241425/
https://www.ncbi.nlm.nih.gov/pubmed/27270430
http://dx.doi.org/10.1038/onc.2016.192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241425/
https://www.ncbi.nlm.nih.gov/pubmed/27270430
http://dx.doi.org/10.1038/onc.2016.192

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